Smallpox was an infectious disease caused by Variola virus, which belongs to the genus Orthopoxvirus. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, making smallpox the only human disease to have been eradicated.
Key Facts
| Subject | Smallpox |
| Category | Eradicated viral disease |
| Reading time | 1 min · Advanced |
| Key date | 1977 |
People Mentioned
Reading level
Audio Summary
Played with your browser's voice. Studio-quality audio can be added with a text-to-speech service.
Ask about this article
📝 Quick Quiz1 / 3
What is "Smallpox" primarily known for?
Vocix Daily — In Your Inbox
Top stories, deep-dive articles, and "On This Day" history — one crisp digest delivered every morning.
Sources & references
Reference material for this entry is drawn from the open encyclopedic record, including Wikipedia , available under the CC BY-SA 4.0 license. Images are credited individually beside each photo.